From I-65 North:

Take I-65 north towards Birmingham
Take exit 261A to merge onto I-20 E/I-59 N toward Gadsden
Take exit 125A for 17th St
Turn left on Reverend Abraham Woods, Jr. Blvd (formerly 8th Ave North)
Turn left on Richard Arrington Jr. Blvd
The museum parking lot is on the left

From I-65 South:

Take I-65 South towards Birmingham
Take exit 261A on the left to merge onto I-20 E/I-59 N
Take exit 125A for 17th St
Take a left on Reverend Abraham Woods, Jr. Blvd (formerly 8th Ave North)
Take a left on Richard Arrington, Jr. Blvd
The museum parking lot is on the left

From I-20 East/59 North:

Take I-20 East/I-59 North towards Birmingham
Take exit 261A on the left to merge onto I-20 E/I-59 N
Take exit 125A for 17th St
Take a left on Reverend Abraham Woods, Jr. Blvd (formerly 8th Ave North)
Take a left on Richard Arrington, Jr. Blvd
The museum parking lot is on the left

From I-20 West:

Take I-20 West towards Birmingham
Take the exit toward I-20 W/I-59 S
Slight right at I-20 W/I-59 S
Take exit 125 on the left for 22nd St
Turn left at 22nd St N
Turn Right at Reverend Abraham Woods, Jr. Blvd (formerly 8th Ave North)
Turn Right at Richard Arrington, Jr. Blvd
The museum parking lot is on the left

From I-59 South:

Take I-59 South Towards Birmingham
Take exit 125 on the left for 22nd St
Turn left at 22nd St N
Turn Right at Reverend Abraham Woods, Jr. Blvd. (formerly 8th Ave North)
Turn Right at Richard Arrington, Jr. Blvd
The museum parking lot is on the left
 
Additional Parking is Available at Deck 2, 801 North 19th Street.